does size (in pixels) matter?

So I am looking for my first android phone, and trying to sift through reviews and forums, comparing specs, and generally driving myself crazy, and its a short trip.
How much am I really going to be able to tell between screen resolutions? For example, the Google Nexus, and the Galaxy 3S are 1280X760, the older Galaxy 2S, is 480X800, and the HTC 1 is 960X540. I am not into watching much in the way of multimedia, and no games that really need high res, so how much can you tell from one resolution to another?
Or is it more about how the screen is made?
Thanks for any help.

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