Android Boot to One Specific App Only

My father has a degenerative condition and is no longer able to see very well and therefore can't read nor watch TV. He was an avid reader and I would like him to be able to have access to audio books to listen to. Because of his eye sight he cannot select books through any interface.

My question is, can I set up a mobile Android device to boot to a audio book reader app (App TBD) only? One button control - on or off - only?

The reader app would be set up to an account that I can add books to when needed locally or from work or home and would sync over wifi?

Thanks as this will greatly improve his quality of life at this point.

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